Near the end of his life, Bob Marley was told by a doctor that he had "more cancer in him than I've seen with a live human being," and that he only had a few months to live, so "he might as well go back out on the road and die there."
Three years earlier, the reggae icon had been diagnosed with melanoma under his toenail in 1977. Doctors removed the nail and the nail bed, but Marley refused to have the toe itself amputated to stop the spread of the disease, insisting that it violated his Rastafarian religious beliefs.
By 1980, the cancer had spread throughout his body, infecting his liver, lungs, and even his brain. Marley played his last show on September 30, 1980, in Pittsburgh, performing Queen's "Another One Bites The Dust" during the soundcheck to the bemusement of his roadies, who didn't know anything was wrong. He died eight months later at the age of 36.